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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
DGKZ
All Species:
5.45
Human Site:
S313
Identified Species:
9.23
UniProt:
Q13574
Number Species:
13
Phosphosite Substitution
Charge Score:
-0.38
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q13574
NP_001099010.1
1117
124128
S313
C
V
A
R
M
L
K
S
V
S
R
R
K
C
A
Chimpanzee
Pan troglodytes
XP_508395
1117
124129
S313
C
V
A
R
M
L
K
S
V
S
R
R
K
C
A
Rhesus Macaque
Macaca mulatta
XP_001102461
1084
120447
L296
P
Q
A
W
S
A
L
L
A
I
E
Q
L
E
K
Dog
Lupus familis
XP_540755
766
85714
A55
V
P
Q
I
P
A
E
A
P
Q
T
Q
K
A
I
Cat
Felis silvestris
Mouse
Mus musculus
Q80UP3
929
104029
K218
C
K
Q
A
Y
H
S
K
V
S
C
F
M
M
Q
Rat
Rattus norvegicus
O08560
929
103991
K218
C
K
Q
A
Y
H
S
K
V
S
C
F
M
L
Q
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513139
955
107141
K244
R
G
R
P
F
V
V
K
P
V
S
S
P
L
M
Chicken
Gallus gallus
NP_001026363
953
106222
A242
E
E
P
C
S
L
G
A
H
A
A
V
V
V
P
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001922445
1086
121319
W312
A
V
I
V
P
P
T
W
I
I
R
V
R
R
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q09103
1457
160124
I578
N
S
R
R
P
I
R
I
V
P
D
W
T
E
N
Honey Bee
Apis mellifera
XP_396522
837
92900
K126
W
I
V
K
L
P
R
K
G
S
F
K
S
S
L
Nematode Worm
Caenorhab. elegans
Q10024
937
105180
L226
L
P
S
E
H
V
W
L
P
S
S
T
G
S
S
Sea Urchin
Strong. purpuratus
XP_796061
815
92455
S104
D
S
F
K
K
A
I
S
K
S
N
A
Y
A
N
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39017
728
79965
K17
F
F
P
S
W
T
S
K
N
P
I
D
T
V
E
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
90.3
65.1
N.A.
78.2
79.3
N.A.
54.7
67.8
N.A.
60.4
N.A.
31.9
31.2
31.6
43.1
Protein Similarity:
100
99.8
91.2
66.6
N.A.
80.5
80.5
N.A.
65.8
74.8
N.A.
70.6
N.A.
46.1
46.2
46.3
55
P-Site Identity:
100
100
6.6
6.6
N.A.
20
20
N.A.
0
6.6
N.A.
13.3
N.A.
13.3
6.6
6.6
13.3
P-Site Similarity:
100
100
13.3
26.6
N.A.
20
20
N.A.
6.6
20
N.A.
26.6
N.A.
26.6
40
26.6
20
Percent
Protein Identity:
N.A.
N.A.
N.A.
20.5
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
32.9
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
0
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
8
0
22
15
0
22
0
15
8
8
8
8
0
15
15
% A
% Cys:
29
0
0
8
0
0
0
0
0
0
15
0
0
15
0
% C
% Asp:
8
0
0
0
0
0
0
0
0
0
8
8
0
0
0
% D
% Glu:
8
8
0
8
0
0
8
0
0
0
8
0
0
15
8
% E
% Phe:
8
8
8
0
8
0
0
0
0
0
8
15
0
0
0
% F
% Gly:
0
8
0
0
0
0
8
0
8
0
0
0
8
0
0
% G
% His:
0
0
0
0
8
15
0
0
8
0
0
0
0
0
0
% H
% Ile:
0
8
8
8
0
8
8
8
8
15
8
0
0
0
8
% I
% Lys:
0
15
0
15
8
0
15
36
8
0
0
8
22
0
8
% K
% Leu:
8
0
0
0
8
22
8
15
0
0
0
0
8
15
8
% L
% Met:
0
0
0
0
15
0
0
0
0
0
0
0
15
8
8
% M
% Asn:
8
0
0
0
0
0
0
0
8
0
8
0
0
0
15
% N
% Pro:
8
15
15
8
22
15
0
0
22
15
0
0
8
0
15
% P
% Gln:
0
8
22
0
0
0
0
0
0
8
0
15
0
0
15
% Q
% Arg:
8
0
15
22
0
0
15
0
0
0
22
15
8
8
0
% R
% Ser:
0
15
8
8
15
0
22
22
0
50
15
8
8
15
8
% S
% Thr:
0
0
0
0
0
8
8
0
0
0
8
8
15
0
0
% T
% Val:
8
22
8
8
0
15
8
0
36
8
0
15
8
15
0
% V
% Trp:
8
0
0
8
8
0
8
8
0
0
0
8
0
0
0
% W
% Tyr:
0
0
0
0
15
0
0
0
0
0
0
0
8
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _